RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-21a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
flow cytometry; PCR; immunofluorescence etc.
Target
NA
Pathway
NA
PubMed ID
Title
Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-B receptor type II mouse
Year
2013
Function
"In mice with tgf- [beta] iir receptor inactivation, mir-21 overexpression was associated with an increase in inflammatory factor activity."